CBD Oil: Facts and Usage of Medical Cannabinoids
For decades across the globe cannabis has been prohibited as a psychoactive drug. However more recently, a tide of research into the therapeutic properties of phytocannabinoids has introduced a niche in the market for cannabidiol (CBD) oil. After years of being masked by the ‘buzz effect’ of the tetrahydrocannabinol (THC), CBD has taken the limelight! Although its molecular mechanisms are yet to be fully investigated, CBD oil has generated a significant amount of interest among scientists – particularly due to the discovery of the medicinal uses of cannabis.
Upon learning that CBD oil is now available to buy over the counter in many health food shops, the first question running through your mind may invariably be “does CBD oil get you high?” With negligible activity at CB1 and CB2 receptors, CBD oil cannot induce the psychological ‘high’ which is commonly associated with THC – the most potent ‘psychoactive’ endogenous cannabinoid of cannabis satvia. However, within the central nervous system CBD oil can provide the user with the therapeutic properties of cannabis, without the adverse health effects associated with THC intake. Thus, CBD can be used to modulate pain and neuropathy in impeding health conditions such as multiple sclerosis, sciatica and fibromyalgia by acting in-vivo within the endocannabinoid system.
CBD has been found to increase the synthesis of analgesic opioids in the body via reductions in oxidative stress and histamine release. CBD is also a potent anti-oxidant – identified by its 2 hydroxyl groups. This allows the body to modulate the release of pro-inflammatory signals, reducing oxidative stress and introducing anti-tumour benefits too.
By restoring the normal balance of oxidative agents and anti-oxidant mechanisms which are frequently disrupted in neuro-degenerative diseases, neuronal survival can be enhanced. Several studies have analysed the effects of cannabidiol within Parkinson’s disease – a disease with a progressive nature characterised by the degeneration of dopaminergic neurones. This condition is most prevalent in adults aged 50+, however it can manifest earlier in life in around 10% of the population.
In Parkinson’s Disease the activation of 5-HT1A receptors by CBD can confer an anti-depressant effect, addressing psychotic activity associated with Parkinson’s and effectively improving the symptoms of the disease. Stimulation of 5-HT1A can initiate both inhibitory and excitatory biological
cascades in the peripheral and central nervous system, therefore CBD oil has the potential to modulate this specific receptor in a range of biological and neurological processes, including anxiety, addiction, appetite, sleep, pain perception, nausea and vomiting.
Here at Hanover Healthfoods, ‘Love CBD’ oil is available to purchase.
These products are made legally in the UK using the hemp flower from plants grown in farms within the European Union. All products are vegan and also free from gluten and lactose. We stock:
• Love Entourage Oil – Containing cannabinoids and terpenes from five different strains of cannabis sativa, this oil provides 800mg of CBD and 0% THC. The recommended dose is 1-4 drops under the tongue per day.
• 4% Love CBD oil – Providing 400mg CBD and 0% THC, this product should be taken before meals and 1-4 drops under the tongue is recommended.
• Love CBD oil spray – This oil contains 400mg of CBD. The recommended dose is 1 spray per day under the tongue.
CBD does affect everyone differently; therefore we recommend that you follow the instructions for taking it, allowing your body to react to it before increasing the dosage.
Pop in-store for a closer look or visit our Featured Product page to order online.